Theoretical Design and Verification (3D Technology)

Various paddle graphs can be directly output from the graph database of the computer via simulation software based on the customer's data. Then 3- objects of the paddles can be printed out through technique hierarchical processing and stack-overlapping assembly. The printed paddle paddle will be tested and verified in the fermenter. Thus, verification period could be shortened greatly, which will improve production efficiency and reduce cost greatly.

The platform for design, simulation, verification and scale up of agitation system: The agitation system is one of the key technology of bioreactor and fermenter, which directly affects the oxygen dissolving, mass transfer, mechanical stress, and air utilization efficiency of the fermentation process. EASTBIO and specialist from related research institute developed a platform for design, simulation, verification and scale up of the agitation system, to specifically serve the customers.

The steps involved:

Roushton radial flow impeller
Characteristic
  1. Six straight blade is fixed on the disc, it's the most classic of radial flow agitator;
  2. Applicable for gas-liquid dispersion;
  3. High power consumption, power number is 4.5-6.2;
  4. Single-phase flow in blade rear trailing vortex;
  5. Gas-liquid two-phase operation leaves cavitation behind.
CD-6 radial flow impeller
Characteristic
  1. Semicircular leaf structure with moderate shearing force;
  2. Medium power consumption, power number Np=3.2;
  3. Flow number Nq=0.61;
  4. Power drops gently under ventilation conditions;
  5. Higher as content, better gas-liquid dispersion, 3 times of ability of rushton paddles, kLa increased by 40%.
BT-6 radial flow impeller
Characteristic
  1. Parabolic blade structure under asymmetric, upper leaves slightly longer than lower ones, moderate shearing;
  2. Low power consumption, power number Np=2.3;
  3. Power drops gently under ventilation conditions;
  4. Efficient dispersion dule covering the ascending gas, high gas holdup;
  5. Excellent gas-liquid dispersion ability, 5 times of ability of Rushton paddle, kLa increased by 60%.
A315 axial flow impeller
Characteristic
  1. Broad leaf structure, effectively control the gas to prevent flooding, applicable for for low viscosity system;
  2. Low power consumption, power number Np=0.75;
  3. Power drops gently under ventilation conditions;
  4. Gas volume is 80% higher than that of Rushton turbine, gas dispersion increased by 4 times;
  5. Moderate shearing, only 1/4 of Rushton turbine.
Asymmetric sawtooth radial flow impeller
Characteristic
  1. Self-designed impeller, Chinese patent ZL200820237972.2;
  2. Parabolic blade structure under asymmetric, gap between upper and lower leaves to prevent trailing vortex;
  3. Low power consumption, power number Np=2.2-2.5;
  4. Power drops gently under ventilation conditions;
  5. High gas holdup, applicable for high viscosity system;
  6. Excellent gas-liquid dispersion ability, 4-6 times of ability of Rushton paddle, kLa increased by 50%.
Six-pitched blade impeller
Characteristic
  1. Six inclind blade turbine structure, has both gas-liquid dispersion ability and axial push function;
  2. Low power consumption, power number Np=2.0-2.2;
  3. Power drops gently under ventilation conditions;
  4. Good gas-liquid dispersion ability, 2-3 times of ability of Rushton paddle, kLa increased by 20%.
Propeller
Characteristic
  1. Tri-blade propeller structure, large axial pushing liquid quantity;
  2. Gas-liquid dispersion capacity is not high;
  3. Low power consumption, power number Np=0.32;
  4. Efficient dispersion dule covering the ascending gas, high gas holdup;
  5. More gently shearing, only 1/5 of shearing force of turbine.
Four-pitched blade axial flow impeller
Characteristic
  1. Four oblique leaf structure, effectively control the gas to prevent flooding, applicable for for medium and high viscosity system;
  2. Low power consumption, power number Np=1.2-1.4;
  3. Power drops gently under ventilation conditions;
  4. Gas volume is 60% higher than that of Rushton turbine, gas dispersion increased by 3 times;
  5. Moderate shearing, only 1/3 of Rushton turbine.